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The biomarker API for health platforms.
Send a CSV or JSON lab panel. Get back normalized biomarkers, domain scores, derived metrics, longitudinal trends, and retest reminders — over REST and MCP.
What the biomarker API handles
Auto-detected markers
Drop in a CSV or JSON panel and the API identifies every marker automatically — glucose, lipids, kidney function, liver enzymes, thyroid, CBC, and more. No schema mapping required. Unknown markers are returned with a flag so you can extend the reference database.
Domain scoring
Every result is scored against established reference ranges into optimal, watch, or needs-attention. Six domains are scored: metabolic, cardiovascular, hepatic, renal, thyroid, and inflammatory. Each domain score includes contributing markers and confidence.
Derived metrics
HOMA-IR for insulin sensitivity, TG:HDL ratio for cardiovascular risk, eGFR for kidney function, and more — all computed from raw lab values automatically. Every derived metric includes the formula and inputs so results are auditable.
Longitudinal trends
Upload multiple panels over time and the API computes direction, deltas, and statistical significance. A marker trending up across three panels triggers a watch flag. Retest cadences are recommended based on rate of change.
Multi-panel reconciliation
Results from different labs, dates, and formats are merged into one timeline. Duplicate markers from the same draw date are reconciled. Your app sees one coherent biomarker history per user.
Lab locator built in
The lab locator endpoint searches Quest and SYNLAB locations by zip or city. Embed a 'Find a lab' flow in your app that returns addresses, hours, and test menus — same API key, same pipeline.
How the pipeline works
From a raw lab panel to scored biomarkers in four steps. Same pipeline runs self-hosted.
Upload
POST a CSV or JSON lab panel. The API auto-detects every marker. Idempotency keys prevent duplicate processing.
Normalize
Every marker is unit-converted, reference-range checked, and scored. Derived metrics like HOMA-IR and eGFR are computed automatically.
Trend
Upload another panel and the API links them. Direction, deltas, and retest windows are computed across your user's entire biomarker history.
Cross-reference
Run multimodal analysis to correlate biomarker trends with genetics and wearables. Everything in one call over REST or MCP.
Combine with
Genomics API →
VCF, WGS, 23andMe, and AncestryDNA ingestion. ClinVar annotation, polygenic risk scores, and pharmacogenomics. Correlate genetic risk with live biomarker data.
Wearable Data API →
WHOOP, Oura, Apple Health, and Garmin aggregation. Normalized HRV, sleep staging, recovery, and strain metrics. See how lifestyle data interacts with your biomarkers.
Questions about the biomarker API
What lab formats do you accept?
CSV and JSON lab panels. The API auto-detects markers — glucose, lipids (HDL, LDL, triglycerides), kidney function (creatinine, eGFR), liver enzymes (ALT, AST, GGT), thyroid panel, CBC, and more. Multi-panel reconciliation merges results from different dates and labs automatically.
Does it interpret the results?
Yes. Every marker is scored against established reference ranges into optimal, watch, or needs-attention. Derived metrics like HOMA-IR, TG:HDL ratio, and eGFR are computed automatically. The analysis returns domain scores across six systems: metabolic, cardiovascular, hepatic, renal, thyroid, and inflammatory.
What about longitudinal tracking?
Upload multiple panels over time and the API computes trends, deltas, and retest cadences automatically. If triglycerides are trending up across three panels, the analysis flags it and recommends a retest window. Every upload is linked to previous results by user ID.
Can users find a lab through the API?
Yes. The lab locator endpoint searches Quest and SYNLAB locations by zip or city. Your app can embed a 'Find a lab near you' flow that returns addresses, hours, and test menus — all through the same API key.
Is the biomarker pipeline open source?
Yes. The full pipeline is on GitHub and runs identically self-hosted or on the hosted API. The hosted version adds EU infrastructure, reference-range databases, and multi-panel reconciliation with no maintenance on your side.
Ingest lab panels from any source without writing a single parser or reference-range lookup.